Publications

Grover D, Chen JY, Xie J, Li J, Changeux JP, Greenspan RJ. (2022) Differential mechanisms underlie trace and delay conditioning in Drosophila. Nature.603(7900):302-308.

Wu ST, Chen JY, Martin V, Ng R, Zhang Y, Grover D, Greenspan RJ, Aljadeff J, Su CY. (2022) Valence opponency in peripheral olfactory processing. Proc Natl Acad Sci U S A. 119(5):e2120134119.

Greenspan RJ. (2021) Learning about quantitative genetics from Marla Sokolowski. J Neurogenet. 35(3):110-111.

Sun R, Delly J, Sereno E, Wong S, Chen X, Wang Y, Huang Y, Greenspan RJ. (2020) Anti-instinctive Learning Behavior Revealed by Locomotion-Triggered Mild Heat Stress in Drosophila. Front Behav Neurosci. 14:41.

Grover D, Katsuki T, Li J, Dawkins TJ, Greenspan RJ. (2020) Imaging brain activity during complex social behaviors in Drosophila with Flyception2. Nat Commun. 11(1):623.

Aimon S, Katsuki T, Jia T, Grosenick L, Broxton M, Deisseroth K, Sejnowski TJ, Greenspan RJ. (2019) Fast near-whole-brain imaging in adult Drosophila during responses to stimuli and behavior. PLoS Biol. 17(2):e2006732.

Gold DA, Katsuki T, Li Y, Yan X, Regulski M, Ibberson D, Holstein T, Steele RE, Jacobs DK, Greenspan RJ. (2019) The genome of the jellyfish Aurelia and the evolution of animal complexity. Nat Ecol Evol. 3(1):96-104.

Srinivasan S, Greenspan RJ, Stevens CF, Grover D. (2018) Deep(er) Learning. J Neurosci. 38(34):7365-7374.

Grover D, Katsuki T, Greenspan RJ. (2016) Flyception: imaging brain activity in freely walking fruit flies. Nat Methods. 13(7):569-72.

Alivisatos AP, Chun M, Church GM, Greenspan RJ, Roukes ML, Yuste R. (2015) A National Network of Neurotechnology Centers for the BRAIN Initiative. Neuron. 88(3):445-8.

Shih CT, Sporns O, Yuan SL, Su TS, Lin YJ, Chuang CC, Wang TY, Lo CC, Greenspan RJ, Chiang AS. (2015) Connectomics-based analysis of information flow in the Drosophila brain. Curr Biol. 2015 May 18;25(10):1249-58.


Shultzaberger RK, Boyd JS, Diamond S, Greenspan RJ, Golden SS. (2015) Giving Time Purpose: The Synechococcus elongatus Clock in a Broader Network Context. Annu Rev Genet. 2015;49:485-505.

Shultzaberger RK, Paddock ML, Katsuki T, Greenspan RJ, Golden SS. (2015) High-throughput and quantitative approaches for measuring circadian rhythms in cyanobacteria using bioluminescence. Methods Enzymol.551:53-72.


Shultzaberger RK, Boyd JS, Katsuki T, Golden SS, Greenspan RJ. (2014) Single mutations in sasA enable a simpler ΔcikA gene network architecture with equivalent circadian properties. Proc Natl Acad Sci U S A. 111(47):E5069-75.

Sejnowski TJ, Poizner H, Lynch G, Gepshtein S, Greenspan RJ.(2014) Prospective Optimization. Proc IEEE Inst Electr Electron Eng. 102(5):10.1109/JPROC.2014.2314297.

Katsuki, T., Greenspan, R.J. (2013) Jellyfish nervous systems. Current Biology 23: R592–R594.

Greenspan, R.J.  (2009)  The landscape of selection, gene interaction, and gene networks. Cold Spring Harbor Symp. Quant. Biol. 74: 131-138.

Foltenyi, K., Greenspan, R.J., Newport, J.W. (2007) Activation of Egf-r and ERK by Rhomboid signaling regulates the consolidation and maintenance of sleep in Drosophila. Nature Neuroscience  10: 1160 – 1167.

Dierick, H.A., Greenspan, R.J. (2007) Serotonin and neuropeptide F have opposite modulatory effects on fly aggression. Nature Genetics 39: 678-682.

Dierick, H.A., Greenspan, R.J. (2006) Molecular analysis of flies selected for aggressive behavior.    Nature Genetics 38: 1023-1031.

Kendler, K.S., Greenspan, R.J. (2006) The nature of genetic influences on behavior: Lessons from “simpler” organisms.  Am. J. Psychiatry 163: 1683-1694.

Andretic, R., van Swinderen, B., Greenspan, R.J. (2005) Dopaminergic modulation of arousal in Drosophila.  Current Biology 15: 1165-1175.

Greenspan, R.J., van Swinderen, B. (2004)  Cognitive consonance: Complex brain functions in the fruit fly and its relatives.  Trends in Neurosciences 27: 707-711.

van Swinderen, B., Greenspan, R.J.  (2003) Salience Modulates 20-30 Hz Brain Activity in Drosophila. Nature Neuroscience 6: 579-586.

Toma, D.P., White, K.P., Hirsch, J., Greenspan, R.J.  (2002)  Identification of genes involved in Drosophila melanogaster geotaxis, a complex behavioral trait.  Nature Genetics 31: 349-353.

Greenspan, R.J. (2001)  The flexible genome.  Nature Reviews Genetics 2: 383-387.

Shaw, P.J., Cirelli, C., Greenspan, R.J., Tononi, G. (2000) Correlates of sleep and waking in Drosophila melanogaster.  Science 287: 1834-1837.

Osborne, K.A., Robichon, A., Burgess, E., Butland, S.,  Shaw, R.A., Coulthard, A., Pererira, Greenspan, R.J., Sokolowski, M.B. (1997) Natural behavior polymorphism due to a cGMP-dependent protein kinase of Drosophila.  Science 277: 834-836.

Ferveur, J.-F., Störtkuhl, K., Stocker, R.F., Greenspan, R.J.  (1995) Genetic feminization of brain structures and changed sexual orientation in male Drosophila melanogaster.   Science  267: 902-905.

Greenspan, R.J. (1995)  Understanding the genetic construction of behavior.  Scientific American  272 (4): 72-78.

Books

Flint, J., Greenspan, R.J., and Kendler, K.S. (2010) How Genes Influence Behavior.  Oxford U. Press: London & New York.

Greenspan, R.J. (2007)  An Introduction to Nervous Systems.  Cold Spring Harbor Laboratory Press: Cold Spring Harbor, NY.